System Center Configuration Manager (SMS4) will be able to act as a remediation server in a NAP environment, which we would expect of course. Given that, with 3rd party agents, SMS can support operating systems other than Windows, all you need is a NAP system health agent (SHA) for your OS of choice and you can support that OS in your NAP/SMS environment.

This animated PowerPoint presentation demonstrates how SMS works with Network Access Protection by stepping through the processes of how a non-compliant computer is restricted until compliant

System Center Configuration Manager (SMS) Network Access Protection Process Flow